“As iron sharpens iron, so a friend sharpens a friend.” Proverbs 27:17 pretty much sums up life at the Cadre Team House, the grinder that never stops. Nothing is off limits, nobody ever sleeps, and privacy doesn’t exist. It’s wholly exhausting and we do it to ourselves.
The great opportunity is to live life to its fullest. The great regret is when you don’t. But regardless the world demands maintenance between stories, and 24 hours is a lot in one day. Life is long and life is short type deal. In Iraq somehow they cram like 72 hours into one day but you only get credit for 24 – at least that’s how it feels when you’re there. Another story. Here, it flies by and you never know what you’re gonna get. Breakfast beers on Tuesday? Sure. Knife-fighting lessons. Yep, every Friday. Screaming speakers? All the time. Except for when Carlos decides Jack Johnson is the standard, those are purring speakers. But then Lou counsels him – poor judgment, that kind of thing – and we’re back in action.
There’s always nails to pound and improvements to make. Then somehow beers start flowing. Carlos usually has some excuse about another work-out or the Jack Johnson riff he’s gotta hear one more time. Then iron sharpens iron and Bud Heavy is the new pre-workout vitamin all natural energy drink. He’s getting stronger by the day, and he’s worked up to the two beer pre-game before a beach run. Soon Bud Heavy will be the new GU shot, complete with all the electrolytes you ever need during your run.
Don’t let all the combat diver Green Beret banter fool you: Chris don’t call him Donnie he hates that is a total softie. You’re lucky if you get to meet him, you’re even luckier if you get to spend some real time with him.
But you’re also glad when he takes a combat nap. It paves the way for two minutes of peace before non combat diver friends (Chris don’t call him Donnie he hates that always points that out) show up. Then dinner is demanded, and anyone but Carlos works the tunes.
Not at all weird, not one bit. And Jack Johnson is purring through speakers somewhere, and it speaks to his soul.
Somehow Lou earned the nickname Big Daddy. Imagine that.
Chris don’t call him Donnie he hates that is always talking. He doesn’t know how to stop. But it gets more interesting when action is involved. “So…I can hit a 9 iron 160 yards. That’s the same distance as Tiger Woods” … uh huh keep talkin’ “though I have to admit [dramatic pause and a big twinkle in his eye] he’s slightly more accurate than I am” .. uh huh takes a real man to admit that while you’re at it why don’t you pin my sister down and smile real big. Thanks bud. Yeah yeah I heard what she said, something about what a liar you are and you can’t prove it.
Yeah, the whole 160 yards thing. Get a chem light out and pour it on a golf ball so we can see how far it goes into the ocean. It’ll be a testament to your manhood for all of us to watch.
And tell us one more time how you used to do this in Afghanistan for hours on end. Then while you’re at it remind us that you’re a badass combat diver except use a bunch of acronyms that nobody cares about.
And…
Uh-oh, windage miscalculation. Chris don’t call him Donnie he hates that and the whack-thump-crack trio are back, and better than ever. Tiger Woods I mean Chris don’t call him Donnie he hates that found the balcony lip instead. The -1 yard 9 iron could have been worse. Luckily the glass door 3 feet behind him was there to stop it.
Shock, embarrassment, and a shattered ego melts down into weakness. And it was worth him doing it just to see him do it. I like collecting stories, and in the iron sharpening world, the more you have to sharpen a friend, the better. And Chris don’t call him Donnie he hates that is on a cold streak these days, and we’re on a hot streak just watching him do things like be himself, then reminding him for days and weeks on end. We’re pretty sure he needs more sharpening, and we’re on the case.
I have no doubt he’ll be back with a vengeance soon. And much like Java, when you play hard and love your life, sometimes life smiles back. The trick is to wear the cone of shame for as long as you have to. But not a day longer. And then get back to doing what you do.
This is like the frat house that never ends. Love it
Awesome post, definitely one of my favorites so far.
Thanks for sharing. Good Livin’
Hahaha, why is poor Java wearing the cone of shame?
Love love love this post! Really cute “non combat diver friends” blue tshirt too 🙂
Jav’s all healed up now. He hits the ocean and the waves and the pavement pretty hard every day. One day he came up limping and it turned out he split his dewclaw (a dog’s thumb) in half. Donnie called it his raptor claw. It was too long and that’s my fault, I just didn’t know I had to trim it from time to time. Anyway, recovery was a process that sucked for both of us. My time at the ocean with him is a little slice of heaven for me, but we had to hold off for a few weeks. Like I said, I’m glad he’s all better now which means I am, too.
That door resembles the GORUCK Crash emblem.
This post made me smile after a super tough day…thanks and keep em comin..
I see a cool little man sporting a GORUCK shirt in this post. When is GORUCK going to launch kid sizes so some of us can shamelessly plug our favorite gear via child advertising? My 6-week old daughter is definitely in need of her own GORUCK anything!
B – big time on our list of things to do this year is the ability to customize t-shirts. Yes, of any size, even little (wo)man sizes. Lots of IT stuff on the back end has to happen first, but we’ll get it right. And yeah, thanks for telling your friends — and no doubt your kids about us 🙂
awesome post! I am also in love with that little guys shirt (need some for my little man). Java in the Man Tie… great photo.
Jason, I can’t get past the FOOD!!!! (and the built-ins!) ok, but curiosity wins… did you just call him Donnie on your comment above? I thought he didn’t like that lol–perhaps you’ve earned the right? 😉 anyway is there a post on why Chris should not be called Donnie? If not, can we get the story during the upcoming NYC- Free Beers and War Stories?. Java with the tie and then the cone!!! I can’t take it! One order for” Java is my homeboy” t-shirt coming right up! Love him.
Chris don’t call him Donnie, he hates that should have been standing on the porch rail. With the ball on the porch rail as well.
When I used to shoot a lot we would stand in chairs, on stools, tree logs, or any off balanced thing we could find. Helped with sight pic.
Great story after a tough day at work.
Also very interested in a black slick gr2. Though you might have to call it an sl2 or something similar. As always great post and see you at a challenge soon.
…and jealousy causes me to turn just a little bit greener…..
Another great post. Thanks jason!
as an expert witness, he can hit a 9 iron 160 yards. of course he has no idea where its going, but he can do it
Great post guys. It makes me miss the boys that much more.
Your writing style is engaging. Enjoy geo news urdu — Urdu headlines and reports. mobile‑friendly. debates, special coverage. quick startup.
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References:
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Comparing Sermorelin and Ipamorelin: The best time to take dianabol before or after workout Choice
for Growth Hormone Release
Sermorelin or Ipamorelin? Deciding the Optimal Peptide Therapy
Sermorelin vs. Ipamorelin: A Side-by-Side Performance Review
Choosing Between Sermorelin and Ipamorelin: What Works Better?
Sermorelin and ipamorelin are two synthetic peptides that have gained
popularity in the realms of anti-aging therapies, athletic performance enhancement, and clinical hormone replacement protocols.
Both compounds act as growth hormone secretagogues (GHS),
meaning they stimulate the pituitary gland to release endogenous human growth hormone (HGH).
Despite sharing this common purpose, their pharmacological profiles
differ markedly, leading to distinct advantages depending on the
user’s goals, tolerance levels, and medical background.
Human Growth Hormone (HGH) Explained
Human growth hormone is a polypeptide produced by the anterior pituitary gland
that plays an essential role in regulating body composition, cell repair, metabolism, and overall vitality.
HGH levels peak during adolescence, gradually declining with age—a process often referred to as somatopause.
The decline contributes to decreased muscle mass, increased adiposity, reduced bone density, diminished immune function, slower wound healing, and a
general sense of fatigue or malaise.
The body’s natural regulation of HGH is tightly controlled by two primary
mechanisms: the hypothalamus releases growth hormone-releasing hormone (GHRH) and somatostatin, while the pituitary gland secretes HGH in response to GHRH stimulation. When circulating HGH levels
rise, a negative feedback loop via insulin-like
growth factor 1 (IGF-1) dampens further secretion, maintaining hormonal balance.
Clinical applications of exogenous HGH have
long included treating growth disorders in children and GH deficiency in adults.
However, the high cost, potential side effects, and legal restrictions surrounding recombinant
HGH have prompted researchers to explore alternative routes that safely stimulate endogenous production rather than administering the hormone directly.
Sermorelin and ipamorelin represent two such alternatives.
Overview of Sermorelin and Ipamorelin
Sermorelin is a synthetic 23-residue peptide that closely mimics the natural GHRH fragment responsible for stimulating HGH release.
Its amino acid sequence is engineered to resist
rapid degradation by peptidases, thereby prolonging its half-life in circulation. When administered subcutaneously or intramuscularly, sermorelin binds to GHRH receptors on pituitary somatotrophs, prompting
the secretion of HGH and IGF-1.
Ipamorelin, by contrast, is a 5-residue hexapeptide that functions as a selective ghrelin receptor agonist.
Ghrelin is often dubbed the “hunger hormone,” but it also
has potent GHS activity. Ipamorelin’s high selectivity for the growth
hormone secretagogue receptor (GHS-R1a) and minimal cross-reactivity with other receptors results in a more focused HGH release profile.
Its short peptide chain confers rapid absorption and quick onset
of action, while its metabolic stability allows sustained stimulation over several
hours.
Both peptides are typically delivered via daily subcutaneous injections.
The dosing regimens differ: sermorelin is often prescribed at 0.2 to 0.5 mg per day, whereas ipamorelin doses
range from 100 to 200 micrograms, reflecting differences in potency and receptor affinity.
Sermorelin vs Ipamorelin: What’s Better?
The question of which peptide is “better” hinges on several factors—clinical
objectives, side-effect tolerance, cost considerations, and personal physiology.
The following comparison highlights key distinctions:
Potency and Dose
– Sermorelin requires a relatively larger dose (hundreds of micrograms) to
achieve comparable HGH peaks. Ipamorelin is markedly more potent;
a few hundred micrograms can produce robust
GH release. This translates into lower injection volumes for ipamorelin, which many users find more convenient.
Selectivity and Side-Effect Profile
– Sermorelin stimulates GHRH receptors, which can indirectly influence other pituitary hormones such as
prolactin or thyroid-stimulating hormone (TSH).
In some individuals, this may lead to mild fluid retention or increased appetite.
Ipamorelin’s receptor specificity limits off-target effects; it rarely alters
prolactin levels and is associated with minimal water retention or edema.
Duration of Action
– Sermorelin’s effect lasts approximately 4–6 hours post-injection, necessitating multiple daily doses for continuous HGH stimulation.
Ipamorelin has a slightly shorter half-life but its receptor activation produces sustained GH release over a comparable timeframe with fewer injections.
Safety and Tolerability
– Both peptides are generally well tolerated in healthy adults.
However, ipamorelin’s minimal impact on other endocrine axes makes
it a safer choice for patients with thyroid disorders or those prone
to fluid overload. Sermorelin may be preferable when a broader
stimulation of pituitary function is desired.
Clinical Evidence
– Multiple randomized controlled trials have demonstrated sermorelin’s efficacy in restoring HGH levels and
improving body composition in GH-deficient adults.
Ipamorelin has been studied less extensively, but emerging data from small cohorts suggest comparable benefits with fewer adverse events.
In sports medicine, ipamorelin is increasingly favored for its discreet dosing and low risk
of detection by anti-doping agencies.
Cost and Accessibility
– The price per milligram of sermorelin can be higher than that of ipamorelin due to synthesis
complexity. Users seeking cost-effective regimens
often opt for ipamorelin, especially when used in larger therapeutic cycles.
Long-Term Use Considerations
– Chronic use of either peptide generally maintains a normal feedback loop; however,
prolonged high doses may blunt pituitary responsiveness over time.
Periodic cycling—treating for several weeks followed by a drug holiday—is recommended to preserve endocrine sensitivity.
Ipamorelin’s shorter dosing schedule may allow more flexible cycling protocols.
Practical Application and Monitoring
When integrating sermorelin or ipamorelin into a therapeutic plan, it
is essential to monitor baseline and post-treatment hormone levels.
A standard protocol involves measuring serum HGH, IGF-1, and insulin sensitivity markers at baseline, mid-cycle, and after completion of therapy.
Adjustments in dose can then be guided by these
laboratory results.
Side effects such as local injection site reactions (pain or erythema), transient headaches, or mild nausea are
common with both peptides but usually resolve within a
few days. Rare adverse events—such as excessive fluid
retention with sermorelin or subtle mood changes with ipamorelin—should prompt reevaluation of dosing or discontinuation.
Conclusion
Sermorelin and ipamorelin offer distinct yet overlapping pathways to stimulate endogenous HGH production. Sermorelin’s
GHRH-mimetic action provides a robust, well-studied approach but may carry a slightly higher
risk of off-target endocrine effects. Ipamorelin’s selective ghrelin receptor agonism delivers potent growth hormone release with a cleaner side-effect profile and lower dosing requirements.
Choosing between them ultimately depends on the individual’s therapeutic
goals—whether maximizing HGH output, minimizing fluid retention, or reducing cost—and their tolerance for potential hormonal
cross-talk. Clinicians and users alike should adopt a personalized regimen, supported by regular endocrine monitoring, to harness the benefits of these
peptides while safeguarding long-term hormonal health.
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References:
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Intratesticular testosterone (ITT) levels are about
50 to 100 occasions greater than in circulation (180) and exogenous
administration severely suppresses this to ranges which
are unable to support spermatogenesis (181). With the exception of its impact on Lp(a), AAS use – particularly use of 17α-alkylated AAS – results in a extra atherogenic
lipid profile (see Table 1). This might help clarify the
outcomes of a population-based cohort study by
which males that examined constructive for AAS had twice the cardiovascular morbidity and mortality rate as those that examined
adverse (149). Nevertheless, it must be acknowledged that causality cannot be drawn from such studies and
further research is necessary to higher explore this detrimental avenue of AAS use
on health. In doing so, you will want to take note of
blood strain cuff dimension. AAS users are extra doubtless to have giant higher arm circumferences, and an inappropriately small
cuff will overestimate blood pressure. The significance of utilizing an acceptable cuff size in a muscular inhabitants was underscored in a trial examining blood stress in a cohort of aggressive bodybuilders (96).
Or they may take the medication in a cycle from no drug to a excessive dose over a period
of weeks to months. Some individuals take legal dietary dietary supplements that have sure steroid hormones also made by the human body.
The physique can turn DHEA into other steroid hormones, including testosterone, estrogen,
and cortisol.
Price Range more if you’re going for the expensive compounds and minimizing your use of ancillary compounds.
Steroids that have extra powerful androgenic properties will be the steroids that can trigger virilization faster
and more severely than steroids that have a lower androgenic ranking.
Some steroids are utterly off-limits to females because of this; they are
too androgenically powerful to be of any constructive benefit to ladies.
By far, essentially the most important and regarding aspect impact for men using steroids
is the greatest way the introduction of synthetic hormones into the physique slows down or usually shuts down, the conventional functioning that produces
testosterone.
This classification makes it illegal to possess, use, buy,
or promote anabolic steroids with no legitimate prescription from a
licensed medical skilled. The use of steroids for non-medical purposes, corresponding to
enhancing athletic performance, is not solely illegal but in addition poses important health risks.
The major cause folks misuse anabolic steroids is to extend lean muscle mass when using
them at the aspect of weight training. Some athletes, bodybuilders
and others misuse these drugs in an try to enhance efficiency and/or improve their bodily
look.
Utilizing or selling these substances and not using a valid prescription can lead
to legal consequences, together with fines and imprisonment.
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In an 8-week cycle, for example, a balanced strategy
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These specifics are actions we can only actually experiment with ourselves, and TAKE NOTE
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The type of steroid is going to be the primary factor concerning
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Their deleterious impact is further augmented by the precise fact, that such tumors have a high incidence in younger people,
the cohort of individuals abusing AAS. Further research are necessary to analyze the potential link between AAS abuse and cancer.
AASs are a recognized cause varied practical disorders,
which can affect liver, cardiovascular, reproductive, musculoskeletal, endocrine,
renal, immunologic or neuropsychiatric techniques. Beyond these deleterious macro-effects, testosterone-derived androgens might act immediately on mobile features, with both genetic or epigenetic elements figuring out toxic,
mutagen, genotoxic and carcinogenic results. AAS can even affect most cancers cell proliferation via genomic and
non-genomic mechanisms, such as the so-called estrogen-dependence mediated
by ER, aromatase expression and IGF-1 production, which might even amplify each other.
Therefore, IGF-1 can be thought of as a well-known most cancers inducer
and promoter affecting each stage of tumor growth, from cellular
proliferation to the metastatic section.
The pro-oxidative results of supraphysiologic-dose AAS reported in people are
in maintaining with findings in numerous animal studies
of the effects of supraphysiologic-dose AAS given over a variety of
exposure conditions (except for years-long
durations). Outcomes from animal research are summarized below in brief and additional examine details are supplied in Table 1.
While anabolic steroids can produce vital advantages,
their results on the body go beyond just muscle growth.
These effects may be broadly categorized into optimistic outcomes and potential risks.
Aside from muscle-building (anabolic) results, steroids also produce androgenic effects, which embrace the event of
male traits similar to deeper voice, facial hair, and increased libido.
He first started using anabolic steroids over thirty years
in the past and has used these brokers in cycles up till the current day.
He had used varied esters of injectable testosterone consistently since starting this
regime.
If each the baseline diameter and the absolute change in diameter can be bigger in the AAS group compared to
the WLC, the decreased FMD might be explained by the bigger baseline diameter within the AAS group.
Nonetheless, on this study, the absolute change in diameter was considerably smaller in the AAS group
compared to the WLC, with no difference in absolute change in move.
This suggests comparable move stimulus for the FMD were applied across each teams, supporting the notion that attenuated FMD response amongst AAS customers reflects endothelial dysfunction. FMD may be measured in different conduit arteries and are mediated
via elevated shear stress on the arterial wall as a result
of increased blood flow32,39. The FMD methodology in giant conduit arteries were first introduced in 1992 when Celemajer et
al. described lowered arterial dilation in response to elevated blood circulate in youngsters
and adults at larger risk of developing CVD39.
To realize the clinical potential of AASs in orthopaedic
surgical procedure, substantial efforts are needed within the preclinical and medical arenas to raised characterize their effects on tissues and establish optimized regimens.
Physicians ought to be conscious of the medical and underground worlds of
AASs and, as with opioids and other potential medicine of abuse,
should not enable the abuse of those medication to
limit their appropriate therapeutic use. The 3-keto stability added
by the 2-hydroxymethylene group tremendously enhances the drug’s anabolic properties.
The action of this agent in androgen-sensitive tissues is very like that of
DHT and is kind of androgenic. Stanozolol is an lively AAS, because of the
stability afforded by the three,2 pyrazole group on the A-ring,
which greatly enhances androgen receptor binding.
In scientific practice, dosages of zero.5–1.zero mg/kg
bodyweight daily are normally prescribed. These may additionally
be effective and demonstrate a decrease frequency and severity of treatment-related
unwanted side effects (71). If first-line treatment with benzoyl peroxide or a topical retinoid yields unsatisfactory results, a low
dosage isotretinoin regimen beneath the supervision of
a dermatologist may be considered in those who refuse to stop their AAS use.
Therapy may additionally forestall pimples scarring which is ready
to, clearly, be everlasting even after stopping AAS use.
Ergogenic uses for AAS in sports, racing, and bodybuilding as performance-enhancing drugs
are controversial due to their opposed effects and the potential to achieve
benefit in physical competitions. In countries the
place AAS are managed substances, there might be typically a black market
during which smuggled, clandestinely manufactured
and even counterfeit medicine are sold to users.
Endocrinologists could additionally be asked to offer documentation (e.g., chart notes,
outcomes of diagnostic studies) of the medical indication for testosterone alternative remedy.
Anabolic-androgenic steroids (AASs) are a large group of molecules
including endogenously produced androgens, corresponding to testosterone, in addition to synthetically
manufactured derivatives. AAS use is widespread because of their ability to enhance muscle progress
for aesthetic functions and athletes’ efficiency, minimizing androgenic effects.
AAS use is very well-liked and 1-3% of US inhabitants have been estimated to be AAS users.
Nonetheless, AASs have unwanted effects, involving all organs, tissues and physique capabilities,
especially long-term toxicity involving the cardiovascular system and the
reproductive system, thereby, their abuse is taken into account a public well being problem.
One Other examine in the UK confirmed that 70% of the clientele
in a well being and health group had been AAS customers [37].
Present knowledge derives largely from the experiences of a small number of physicians who’ve worked with patients undergoing steroid withdrawal.
They have learned that, in general, supportive remedy combined with training about potential withdrawal
symptoms is sufficient in some circumstances. The most
important distinction is that AAS aren’t euphorigenic, that means
they do not trigger fast will increase within the neurotransmitter dopamine, which is answerable for the “high” that always drives substance
abuse behaviors.
Tbol is a steroid that is not highly valued by bodybuilders
but extra so by performance athletes, because of its capacity to reinforce muscle endurance, strength,
and restoration. Noticeable features in pace and energy can be
anticipated with this steroid, making it fascinating for sports activities athletes,
which is why this steroid is infamous for its past use by East German Olympic athletes within the Nineteen Seventies and Eighties.
For chopping functions, a better dosage holds little benefit however a better
threat of unwanted effects. An 8-week cutting cycle with Equipoise is beneficial, together with if you are doing an extended
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Equipoise excels at slicing and is excellent at helping retain lean muscle
and provide a basic enchancment in physique conditioning.
Strength, muscle endurance, and recovery improvements are
areas in which Equipoise provides distinctive benefits.
References:
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